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B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis
OBJECTIVES: TNFSF4 (encodes OX40L) is a susceptibility locus for systemic lupus erythematosus (SLE). Risk alleles increase TNFSF4 expression in cell lines, but the mechanism linking this effect to disease is unclear, and the OX40L-expressing cell types mediating the risk are not clearly established....
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| Veröffentlicht in: | Ann Rheum Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMJ Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705841/ https://ncbi.nlm.nih.gov/pubmed/28818832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-211499 |
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