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Predicted MHC peptide binding promiscuity explains MHC class I ‘hotspots’ of antigen presentation defined by mass spectrometry eluted ligand data

Peptides that bind to and are presented by MHC class I and class II molecules collectively make up the immunopeptidome. In the context of vaccine development, an understanding of the immunopeptidome is essential, and much effort has been dedicated to its accurate and cost‐effective identification. C...

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Publicat a:Immunology
Autors principals: Jappe, Emma Christine, Kringelum, Jens, Trolle, Thomas, Nielsen, Morten
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002231/
https://ncbi.nlm.nih.gov/pubmed/29446062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12905
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