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Predicted MHC peptide binding promiscuity explains MHC class I ‘hotspots’ of antigen presentation defined by mass spectrometry eluted ligand data

Peptides that bind to and are presented by MHC class I and class II molecules collectively make up the immunopeptidome. In the context of vaccine development, an understanding of the immunopeptidome is essential, and much effort has been dedicated to its accurate and cost‐effective identification. C...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Jappe, Emma Christine, Kringelum, Jens, Trolle, Thomas, Nielsen, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002231/
https://ncbi.nlm.nih.gov/pubmed/29446062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12905
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