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NetMHCpan 4.0: Improved peptide-MHC class I interaction predictions integrating eluted ligand and peptide binding affinity data

Cytotoxic T cells are of central importance in the immune system’s response to disease. They recognize defective cells by binding to peptides presented on the cell surface by MHC (major histocompatibility complex) class I molecules. Peptide binding to MHC molecules is the single most selective step...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Jurtz, Vanessa, Paul, Sinu, Andreatta, Massimo, Marcatili, Paolo, Peters, Bjoern, Nielsen, Morten
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679736/
https://ncbi.nlm.nih.gov/pubmed/28978689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700893
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