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Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate–carbohydrate interactions

The mucin-type O-glycome in cancer aberrantly expresses the truncated glycans Tn (GalNAcα1-Ser/Thr) and STn (Neu5Acα2,6GalNAcα1-Ser/Thr). However, the role of Tn and STn in cancer and other diseases is not well understood. Our recent discovery of the self-binding properties (carbohydrate–carbohydrat...

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Bibliografiska uppgifter
I publikationen:Glycobiology
Huvudupphovsmän: Sletmoen, Marit, Gerken, Thomas A, Stokke, Bjørn T, Burchell, Joy, Brewer, C Fred
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001880/
https://ncbi.nlm.nih.gov/pubmed/29618060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwy032
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