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Enhanced self-association of mucins possessing the T and Tn carbohydrate cancer antigens at the single-molecule level
Mucins are linear O-glycosylated glycoproteins involved in inflammation, cell adhesion and tumorigenesis. Cancer associated mucins often possess increased expression of the T (Galβ1,3GalNAcαThr/Ser) and Tn (GalNAcαThr/Ser) cancer antigens, which are diagnotic markers for several cancers including co...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364602/ https://ncbi.nlm.nih.gov/pubmed/22428527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300135h |
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