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Enhanced self-association of mucins possessing the T and Tn carbohydrate cancer antigens at the single-molecule level

Mucins are linear O-glycosylated glycoproteins involved in inflammation, cell adhesion and tumorigenesis. Cancer associated mucins often possess increased expression of the T (Galβ1,3GalNAcαThr/Ser) and Tn (GalNAcαThr/Ser) cancer antigens, which are diagnotic markers for several cancers including co...

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Bibliografski detalji
Glavni autori: Haugstad, Kristin E., Gerken, Thomas A., Stokke, Bjørn T., Dam, Tarun K., Brewer, C. Fred, Sletmoen, Marit
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364602/
https://ncbi.nlm.nih.gov/pubmed/22428527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300135h
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