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Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate–carbohydrate interactions
The mucin-type O-glycome in cancer aberrantly expresses the truncated glycans Tn (GalNAcα1-Ser/Thr) and STn (Neu5Acα2,6GalNAcα1-Ser/Thr). However, the role of Tn and STn in cancer and other diseases is not well understood. Our recent discovery of the self-binding properties (carbohydrate–carbohydrat...
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| Pubblicato in: | Glycobiology |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6001880/ https://ncbi.nlm.nih.gov/pubmed/29618060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwy032 |
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