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Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma

In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this mutation grows, so too does the number of mutation subtypes reported in th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:CNS Oncol
Main Authors: Lu, Victor M, McDonald, Kerrie L
Format: Artigo
Jezik:Inglês
Izdano: Future Medicine Ltd 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001689/
https://ncbi.nlm.nih.gov/pubmed/29303363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2017-0019
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