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Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma

In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this mutation grows, so too does the number of mutation subtypes reported in th...

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Foilsithe in:CNS Oncol
Main Authors: Lu, Victor M, McDonald, Kerrie L
Formáid: Artigo
Teanga:Inglês
Foilsithe: Future Medicine Ltd 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001689/
https://ncbi.nlm.nih.gov/pubmed/29303363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2017-0019
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