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Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma

In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this mutation grows, so too does the number of mutation subtypes reported in th...

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Detalles Bibliográficos
Publicado en:CNS Oncol
Main Authors: Lu, Victor M, McDonald, Kerrie L
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001689/
https://ncbi.nlm.nih.gov/pubmed/29303363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2017-0019
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