Atg7 inhibits Warburg effect by suppressing PKM2 phosphorylation resulting reduced epithelial-mesenchymal transition

Metabolic reprogramming is a distinct hallmark in tumorigenesis. Autophagy can rewire cell metabolism by regulating intracellular homeostasis. Warburg effect is a specific energy metabolic process that allows tumor cells to metabolize glucose via glycolysis into lactate even in the presence of oxyge...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Feng, Yanling, Liu, Jingwei, Guo, Wendong, Guan, Yi, Xu, Hongde, Guo, Qiqiang, Song, Xiaoyu, Yi, Fei, Liu, Ting, Zhang, Wenyu, Dong, Xiang, Cao, Longyue L., O'Rourke, Brian P., Cao, Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001680/
https://ncbi.nlm.nih.gov/pubmed/29910687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.26077
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