FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1α/CEACAM5 functional axis

F-box and WD repeat domain-containing 7 (FBW7) functions as a major tumor suppressor by targeting oncoproteins for degradations. FBW7 has been reported to be one of the most frequently mutated genes in colorectal cancer (CRC). However, its roles and possible mechanisms in the development of CRC are...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Biol Sci
Auteurs principaux: Li, Qingguo, Li, Yaqi, Li, Jing, Ma, Yanlei, Dai, Weixing, Mo, Shaobo, Xu, Ye, Li, Xinxiang, Cai, Sanjun
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001674/
https://ncbi.nlm.nih.gov/pubmed/29910683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.24505
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires