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Discontinuation and dose adjustment of metoprolol after metoprolol‐paroxetine/fluoxetine co‐prescription in Dutch elderly

PURPOSE: Co‐prescription of paroxetine/fluoxetine (a strong CYP2D6 inhibitor) in metoprolol (a CYP2D6 substrate) users is common, but data on the clinical consequences of this drug‐drug interaction are limited and inconclusive. Therefore, we assessed the effect of paroxetine/fluoxetine initiation on...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pharmacoepidemiol Drug Saf
Päätekijät: Bahar, Muh. Akbar, Wang, Yuanyuan, Bos, Jens H.J., Wilffert, Bob, Hak, Eelko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001522/
https://ncbi.nlm.nih.gov/pubmed/29575226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pds.4422
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