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Discontinuation and dose adjustment of metoprolol after metoprolol‐paroxetine/fluoxetine co‐prescription in Dutch elderly

PURPOSE: Co‐prescription of paroxetine/fluoxetine (a strong CYP2D6 inhibitor) in metoprolol (a CYP2D6 substrate) users is common, but data on the clinical consequences of this drug‐drug interaction are limited and inconclusive. Therefore, we assessed the effect of paroxetine/fluoxetine initiation on...

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Dades bibliogràfiques
Publicat a:Pharmacoepidemiol Drug Saf
Autors principals: Bahar, Muh. Akbar, Wang, Yuanyuan, Bos, Jens H.J., Wilffert, Bob, Hak, Eelko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001522/
https://ncbi.nlm.nih.gov/pubmed/29575226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pds.4422
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