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The impact of CYP2D6 mediated drug–drug interaction: a systematic review on a combination of metoprolol and paroxetine/fluoxetine

AIM: Metoprolol (a CYP2D6 substrate) is often co‐prescribed with paroxetine/fluoxetine (a CYP2D6 inhibitor) because the clinical relevance of this drug–drug interaction (DDI) is still unclear. This review aimed to systematically evaluate the available evidence and quantify the clinical impact of the...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Bahar, Muh. Akbar, Kamp, Jasper, Borgsteede, Sander D., Hak, Eelko, Wilffert, Bob
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255988/
https://ncbi.nlm.nih.gov/pubmed/30248178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13741
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