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ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells

Inducible costimulator (ICOS) plays an important role in the suppressive immunity mediated by regulatory T cells (Tregs), but the molecular regulation mechanism is not well known. Here we performed a study to explore the possible mechanism by which ICOS regulates the suppressive functions and surviv...

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Bibliografske podrobnosti
izdano v:Int J Med Sci
Main Authors: Chen, Qianmei, Mo, Lijun, Cai, Xiangsheng, Wei, Lili, Xie, Zhengneng, Li, Hongwei, Li, Jinlong, Hu, Zhiming
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001412/
https://ncbi.nlm.nih.gov/pubmed/29910670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.23940
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