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Dysregulated ICOS(+) proinflammatory and suppressive regulatory T cells in patients with rheumatoid arthritis

Regulatory T cells (Tregs) serve an important role in the pathogenesis of rheumatoid arthritis (RA) by regulating autoimmunity and inflammation. Humans and mice contain inducible T-cell costimulator-positive (ICOS(+)) Tregs, although their role in RA is unclear. A total of 33 patients with RA and 17...

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Bibliografiske detaljer
Udgivet i:Exp Ther Med
Main Authors: Wang, Hong-Xia, Kang, Xia, Chu, Shuai, Li, Haixia, Li, Xin, Yin, Xiaofeng, Qiu, Yu-Rong, Lai, Weinan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143914/
https://ncbi.nlm.nih.gov/pubmed/30233732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6657
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