Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis

OBJECTIVE: Premature senescence of lymphocytes is a hallmark of inflammatory rheumatic diseases such as rheumatoid arthritis (RA). Early T-cell aging affects conventional T-cells but is presumably not limited to this cell population; rather it might also occur in the regulatory T-cells (Tregs) compa...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fessler, Johannes, Raicht, Andrea, Husic, Rusmir, Ficjan, Anja, Schwarz, Christine, Duftner, Christina, Schwinger, Wolfgang, Graninger, Winfried B., Stradner, Martin H., Dejaco, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357868/
https://ncbi.nlm.nih.gov/pubmed/28373873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00300
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