A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes

OBJECTIVE: Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and T2D. METHODS: A computational framework (miR-QTL-...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Gottmann, Pascal, Ouni, Meriem, Saussenthaler, Sophie, Roos, Julian, Stirm, Laura, Jähnert, Markus, Kamitz, Anne, Hallahan, Nicole, Jonas, Wenke, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald, Blüher, Matthias, Fischer-Posovszky, Pamela, Vogel, Heike, Schürmann, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001404/
https://ncbi.nlm.nih.gov/pubmed/29605715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.03.005
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