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Epigenetic Changes in Islets of Langerhans Preceding the Onset of Diabetes

The identification of individuals with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention. Here, we used a translational approach and prediction criteria to identify changes in DNA methylation visible before the development of T2D. Islets of Langerhans were isolated from g...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Ouni, Meriem, Saussenthaler, Sophie, Eichelmann, Fabian, Jähnert, Markus, Stadion, Mandy, Wittenbecher, Clemens, Rönn, Tina, Zellner, Lisa, Gottmann, Pascal, Ling, Charlotte, Schulze, Matthias B., Schürmann, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576562/
https://ncbi.nlm.nih.gov/pubmed/32816961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0204
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