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Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation
Beta-cell apoptosis and failure to induce beta-cell regeneration are hallmarks of type 2-like diabetes in mouse models. Here we show that islets from obese, diabetes-susceptible New Zealand Obese (NZO) mice, in contrast to diabetes-resistant C57BL/6J (B6)-ob/ob mice, do not proliferate in response t...
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| Publicat a: | PLoS Genet |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562707/ https://ncbi.nlm.nih.gov/pubmed/26348837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005506 |
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