A vast genomic deletion in the C56BL/6 genome affects different genes within the Ifi200 cluster on chromosome 1 and mediates obesity and insulin resistance

BACKGROUND: Obesity, the excessive accumulation of body fat, is a highly heritable and genetically heterogeneous disorder. The complex, polygenic basis for the disease consisting of a network of different gene variants is still not completely known. RESULTS: In the current study we generated a BAC l...

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Publicat a:BMC Genomics
Autors principals: Vogel, Heike, Jähnert, Markus, Stadion, Mandy, Matzke, Daniela, Scherneck, Stephan, Schürmann, Annette
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312539/
https://ncbi.nlm.nih.gov/pubmed/28201990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3552-6
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