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Exceptionally rapid oxime and hydrazone formation promoted by catalytic amine buffers with low toxicity

Hydrazone and oxime bond formation between α-nucleophiles (e.g. hydrazines, alkoxy-amines) and carbonyl compounds (aldehydes and ketones) is convenient and is widely applied in multiple fields of research. While the reactants are simple, a substantial drawback is the relatively slow reaction at neut...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Larsen, Dennis, Kietrys, Anna M., Clark, Spencer A., Park, Hyun Shin, Ekebergh, Andreas, Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001384/
https://ncbi.nlm.nih.gov/pubmed/29997880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01082j
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