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Fluorescence Quenchers for Hydrazone and Oxime Orthogonal Bioconjugation

We describe the synthesis and properties of new fluorescence quenchers containing aldehyde, hydrazine and aminooxy groups, allowing convenient bioconjugation as oximes or hydrazones. Conjugation to oligonucleotides proceeded in high yield with aniline as catalyst. Kinetics studies of conjugation sho...

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Bibliografiska uppgifter
Huvudupphovsmän: Crisalli, Pete, Hernández, Armando R., Kool, Eric T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447104/
https://ncbi.nlm.nih.gov/pubmed/22913527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300344b
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