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Fluorescence Quenchers for Hydrazone and Oxime Orthogonal Bioconjugation
We describe the synthesis and properties of new fluorescence quenchers containing aldehyde, hydrazine and aminooxy groups, allowing convenient bioconjugation as oximes or hydrazones. Conjugation to oligonucleotides proceeded in high yield with aniline as catalyst. Kinetics studies of conjugation sho...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447104/ https://ncbi.nlm.nih.gov/pubmed/22913527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300344b |
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