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Importance of ortho Proton Donors in Catalysis of Hydrazone Formation

[Image: see text] Anthranilic acids were recently reported as superior catalysts for hydrazone and oxime formation compared to aniline, the classic catalyst for these reactions. Here, alternative proton donors were examined with varied pK(a) in an effort to enhance activity at biological pH. The exp...

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Detalhes bibliográficos
Main Authors: Crisalli, Pete, Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618716/
https://ncbi.nlm.nih.gov/pubmed/23477719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol400427x
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