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New Organocatalyst Scaffolds with High Activity in Promoting Hydrazone and Oxime Formation at Neutral pH

[Image: see text] The discovery of two new classes of catalysts for hydrazone and oxime formation in water at neutral pH, namely 2-aminophenols and 2-(aminomethyl)benzimidazoles, is reported. Kinetics studies in aqueous solutions at pH 7.4 revealed rate enhancements up to 7-fold greater than with cl...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Larsen, Dennis, Pittelkow, Michael, Karmakar, Saswata, Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301078/
https://ncbi.nlm.nih.gov/pubmed/25545888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol503372j
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