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Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose

BACKGROUND: For glioblastoma (GBM) treatments to be effective in vivo, understanding the effects of the tumor microenvironment is imperative. In traditional cell culture conditions, glucose concentrations do not model physiologic levels, nor the diminished concentrations found in tumor niches. We th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomark Res
Egile Nagusiak: Walker, Kiera, Boyd, Nathaniel H., Anderson, Joshua C., Willey, Christopher D., Hjelmeland, Anita B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001119/
https://ncbi.nlm.nih.gov/pubmed/29946469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-018-0136-9
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