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Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing

The use of patient-derived xenografts for modeling cancers has provided important insight into cancer biology and drug responsiveness. However, they are time consuming, expensive, and labor intensive. To overcome these obstacles, many research groups have turned to spheroid cultures of cancer cells....

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Gilbert, Ashley N., Shevin, Rachael S., Anderson, Joshua C., Langford, Catherine P., Eustace, Nicholas, Gillespie, G. Yancey, Singh, Raj, Willey, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927781/
https://ncbi.nlm.nih.gov/pubmed/27341166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54026
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