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Magnolin promotes autophagy and cell cycle arrest via blocking LIF/Stat3/Mcl-1 axis in human colorectal cancers

Magnolin is a multi-bioactive natural compound that possesses underlying anti-cancer properties. However, the mechanisms underlying remain to be elucidated. Here, we report the role of magnolin in suppressing human colorectal cancer (CRC) cells via activating autophagy and cell cycle arrest in vitro...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yu, Haiyang, Yin, Shuangshuang, Zhou, Shiyue, Shao, Yingying, Sun, Jiachen, Pang, Xu, Han, Lifeng, Zhang, Yi, Gao, Xiumei, Jin, Chengyun, Qiu, Yuling, Wang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999973/
https://ncbi.nlm.nih.gov/pubmed/29899555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0660-4
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