Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

TYK2 is a member of the JAK family of tyrosine kinases that is involved in chromosomal translocation-induced fusion proteins found in anaplastic large cell lymphomas (ALCL) that lack rearrangements activating the anaplastic lymphoma kinase (ALK). Here we demonstrate that TYK2 is highly expressed in...

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Bibliografiset tiedot
Julkaisussa:Leukemia
Päätekijät: Prutsch, Nicole, Gurnhofer, Elisabeth, Suske, Tobias, Liang, Huan Chang, Schlederer, Michaela, Roos, Simone, Wu, Lawren C., Simonitsch-Klupp, Ingrid, Alvarez-Hernandez, Andrea, Kornauth, Christoph, Leone, Dario A., Svinka, Jasmin, Eferl, Robert, Limberger, Tanja, Aufinger, Astrid, Shirsath, Nitesh, Wolf, Peter, Hielscher, Thomas, Sternberg, Christina, Aberger, Fritz, Schmoellerl, Johannes, Stoiber, Dagmar, Strobl, Birgit, Jäger, Ulrich, Staber, Philipp B., Grebien, Florian, Moriggl, Richard, Müller, Mathias, Inghirami, Giorgio G., Sanda, Takaomi, Look, A. Thomas, Turner, Suzanne D., Kenner, Lukas, Merkel, Olaf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076043/
https://ncbi.nlm.nih.gov/pubmed/30131584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0239-1
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