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Glaucocalyxin A exerts anticancer effect on osteosarcoma by inhibiting GLI1 nuclear translocation via regulating PI3K/Akt pathway

Osteosarcoma, the most common malignant bone tumor with recurring disease or lung metastases, has become one of the leading causes of death in humans. In the current study, we made an investigation on the anticancer effect of glaucocalyxin A, a bioactive ent-kauranoid diterpenoid isolated from Rabdo...

詳細記述

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書誌詳細
出版年:Cell Death Dis
主要な著者: Zhu, Jianwei, Sun, Yang, Lu, Ying, Jiang, Xiubo, Ma, Bo, Yu, Lisha, Zhang, Jie, Dong, Xiaochen, Zhang, Qi
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999605/
https://ncbi.nlm.nih.gov/pubmed/29899333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0684-9
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