Oridonin exerts anticancer effect on osteosarcoma by activating PPAR-γ and inhibiting Nrf2 pathway

Osteosarcoma is the most common high-grade human primary malignant bone sarcoma with lower survival in the past decades. Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been proved to possess potent anti-cancer effects. However, its potential mechanism still remains not fully...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lu, Ying, Sun, Yang, Zhu, Jianwei, Yu, Lisha, Jiang, Xiubo, Zhang, Jie, Dong, Xiaochen, Ma, Bo, Zhang, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849031/
https://ncbi.nlm.nih.gov/pubmed/29323103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0031-6
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