Evaluation of D-isomers of 4-borono-2-(18)F-fluoro-phenylalanine and O-(11)C-methyl-tyrosine as brain tumor imaging agents: a comparative PET study with their L-isomers in rat brain glioma

BACKGROUND: The potential of the D-isomerization of 4-borono-2-(18)F-fluoro-phenylalanine ((18)F-FBPA) to improve its target tumor to non-target normal brain tissue ratio (TBR) was evaluated in rat brain glioma and compared with those of L- and D-(11)C-methyl-tyrosine ((11)C-CMT). The L- or D-isomer...

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Bibliografiske detaljer
Udgivet i:EJNMMI Res
Main Authors: Kanazawa, Masakatsu, Nishiyama, Shingo, Hashimoto, Fumio, Kakiuchi, Takeharu, Tsukada, Hideo
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999598/
https://ncbi.nlm.nih.gov/pubmed/29900520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0404-6
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