Inflammatory-induced spinal dorsal horn neurons hyperexcitability is mediated by P2X4 receptors

INTRODUCTION: Purinergic ionotropic P2X receptors (P2RX) are involved in normal and pathological pain transmission. Among them, P2X4 are expressed in dorsal root ganglion and in the spinal cord. Their activation during nerve injury or chronic peripheral inflammation modifies pain sensitivity that le...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Pain Rep
Asıl Yazarlar: Aby, Franck, Whitestone, Sara, Landry, Marc, Ulmann, Lauriane, Fossat, Pascal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wolters Kluwer 2018
Konular:
Basic Science
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999414/
https://ncbi.nlm.nih.gov/pubmed/29922748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000660
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