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Discovery of Prostamide F(2α) and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability

It was suggested that endocannabinoids are metabolized by cyclooxygenase (COX)-2 in the spinal cord of rats with kaolin/λ-carrageenan-induced knee inflammation, and that this mechanism contributes to the analgesic effects of COX-2 inhibitors in this experimental model. We report the development of a...

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Bibliografiske detaljer
Main Authors: Gatta, Luisa, Piscitelli, Fabiana, Giordano, Catia, Boccella, Serena, Lichtman, Aron, Maione, Sabatino, Di Marzo, Vincenzo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283613/
https://ncbi.nlm.nih.gov/pubmed/22363560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031111
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