Evaluation of current prediction models for Lynch syndrome: updating the PREMM5 model to identify PMS2 mutation carriers

Until recently, no prediction models for Lynch syndrome (LS) had been validated for PMS2 mutation carriers. We aimed to evaluate MMRpredict and PREMM5 in a clinical cohort and for PMS2 mutation carriers specifically. In a retrospective, clinic-based cohort we calculated predictions for LS according...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Fam Cancer
Päätekijät: Goverde, A., Spaander, M. C. W., Nieboer, D., van den Ouweland, A. M. W., Dinjens, W. N. M., Dubbink, H. J., Tops, C. J., ten Broeke, S. W., Bruno, M. J., Hofstra, R. M. W., Steyerberg, E. W., Wagner, A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999171/
https://ncbi.nlm.nih.gov/pubmed/28933000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-017-0039-1
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