Adenosine A(2A) receptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis

The axonal guidance proteins semaphorin (Sema)4D and Sema3A play important roles in communication between osteoclasts and osteoblasts. As stimulation of adenosine A(2A) receptors (A2AR) regulates both osteoclast and osteoblast function, we asked whether A2AR regulates both osteoclast and osteoblast...

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Bibliographic Details
Published in:FASEB J
Main Authors: Mediero, Aránzazu, Wilder, Tuere, Shah, Lopa, Cronstein, Bruce N.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998975/
https://ncbi.nlm.nih.gov/pubmed/29394106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700217R
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