Načítá se...
Decomposing dynamical couplings in mutated scFv antibody fragments into stabilizing and destabilizing effects
Conformational fluctuations within scFv antibodies are characterized by a novel perturbation-response decomposition of molecular dynamics trajectories. Both perturbation and response profiles are stratified into stabilizing and destabilizing conditions. The linker between the VH and VL domains exhib...
Uloženo v:
| Vydáno v: | J Am Chem Soc |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5998336/ https://ncbi.nlm.nih.gov/pubmed/29139290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09268 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|