Nalaganje...
Decomposing dynamical couplings in mutated scFv antibody fragments into stabilizing and destabilizing effects
Conformational fluctuations within scFv antibodies are characterized by a novel perturbation-response decomposition of molecular dynamics trajectories. Both perturbation and response profiles are stratified into stabilizing and destabilizing conditions. The linker between the VH and VL domains exhib...
Shranjeno v:
| izdano v: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5998336/ https://ncbi.nlm.nih.gov/pubmed/29139290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09268 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|