Suppression of mitochondrial oxygen metabolism mediated by the transcription factor HIF-1 alleviates propofol-induced cell toxicity

A line of studies strongly suggest that the intravenous anesthetic, propofol, suppresses mitochondrial oxygen metabolism. It is also indicated that propofol induces the cell death in a reactive oxygen species (ROS)-dependent manner. Because hypoxia-inducible factor 1 (HIF-1) is a transcription facto...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Sumi, Chisato, Okamoto, Akihisa, Tanaka, Hiromasa, Kusunoki, Munenori, Shoji, Tomohiro, Uba, Takeo, Adachi, Takehiko, Iwai, Teppei, Nishi, Kenichiro, Harada, Hiroshi, Bono, Hidemasa, Matsuo, Yoshiyuki, Hirota, Kiichi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997661/
https://ncbi.nlm.nih.gov/pubmed/29895831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27220-8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares