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Mimetic peptide of ubiquitin-interacting motif of epsin as a cancer therapeutic-perspective in brain tumor therapy through regulating VEGFR2 signaling

Epsins, endocytic adaptor proteins required for internalization of ubiquitylated receptors, are generally upregulated in human cancers. It has been characterized that mice deficient of epsins in the endothelium inhibit tumor growth by dysregulating vascular endothelial growth factor receptor-2 (VEGF...

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Detalhes bibliográficos
Publicado no:Vessel Plus
Main Authors: Dong, Yunzhou, Wu, Hao, Dong, Jerry, Song, Kai, Rahman, Habibunnabi Ashiqur, Towner, Rheal, Chen, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997290/
https://ncbi.nlm.nih.gov/pubmed/29905336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/2574-1209.2016.01
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