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Understanding Site Selectivity in the Palladium-Catalyzed Cross-Coupling of Allenylsilanolates

Allenylsilanolates can undergo cross-coupling at the α- or γ-terminus, and site selectivity appears to be determined by the intrinsic transmetalation mechanism. Fine-tuning of concentration, nucleophilicity, and steric bulk of the silanolate moiety allows for the selective formation of one isomer ov...

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Bibliografische gegevens
Gepubliceerd in:Synlett
Hoofdauteurs: Denmark, Scott E., Ambrosi, Andrea
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997285/
https://ncbi.nlm.nih.gov/pubmed/29904234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1588471
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