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A single cell Wnt signaling niche maintains stemness of alveolar type 2 cells
Lung alveoli are lined by squamous alveolar epithelial type 1 (AT1) epithelial cells that facilitate gas exchange, and neighboring AT2 cells that synthesize and secrete surfactant. Alveoli are maintained by intermittent activation of rare ‘bifunctional’ AT2 cells that retain surfactant biosynthesis...
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| Publicado en: | Science |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997265/ https://ncbi.nlm.nih.gov/pubmed/29420258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam6603 |
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