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Alveolar progenitor and stem cells in lung development, renewal and cancer

Alveoli are gas-exchange sacs lined by squamous alveolar type (AT) 1 cells and cuboidal, surfactant-secreting AT2 cells. Classical studies suggested AT1 arise from AT2 cells, but recent studies propose other sources. Here we use molecular markers, lineage tracing, and clonal analysis to map alveolar...

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Autors principals: Desai, Tushar J., Brownfield, Douglas G., Krasnow, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013278/
https://ncbi.nlm.nih.gov/pubmed/24499815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12930
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