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The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses

Guanine nucleotide Exchange Factors (GEFs) are responsible for mediating GDP/GTP exchange for specific small G proteins, such as Rac. There has been substantial evidence for the involvement of Rac-GEFs in the control of cancer cell migration and metastatic progression. We have previously established...

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Bibliografiske detaljer
Udgivet i:Small GTPases
Main Authors: Kazanietz, Marcelo G., Barrio-Real, Laura, Casado-Medrano, Victoria, Baker, Martin J., Lopez-Haber, Cynthia
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997144/
https://ncbi.nlm.nih.gov/pubmed/27588611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1221273
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