APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults

OBJECTIVE: To examine the association of the APOE ε2ε4 genotype with incident Alzheimer disease (AD), mild cognitive impairment (MCI), cognitive decline, and AD pathology in older adults. METHODS: We used data from 2,151 older adults of European ancestry who were free of dementia at baseline and und...

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Veröffentlicht in:Neurology
Hauptverfasser: Oveisgharan, Shahram, Buchman, Aron S., Yu, Lei, Farfel, Jose, Hachinski, Vladimir, Gaiteri, Chris, De Jager, Philip L., Schneider, Julie A., Bennett, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996834/
https://ncbi.nlm.nih.gov/pubmed/29752306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005677
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