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Effect of APOE Genotype Status on Targeted Clinical Trials Outcomes and Efficiency in Dementia and MCI due to AD
BACKGROUND: Apolipoprotein ε4 genotype has been recommended as a potential inclusion or exclusion criterion in targeted clinical trials for Alzheimer disease and MCI due to AD, and implemented in trials of immunotherapeutic agents. METHODS: We tested this recommendation with clinical trials simulati...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900604/ https://ncbi.nlm.nih.gov/pubmed/23712001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2013.03.003 |
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