The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation

INTRODUCTION: Cardiomyocyte remodelling in atrial fibrillation (AF) has been associated with both oxidative stress and endoplasmic reticulum (ER) stress and is accompanied by a complex transcriptional regulation. Here, we investigated the role the oxidative stress and ER stress responsive bZIP trans...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Freundt, Johanna K., Frommeyer, Gerrit, Wötzel, Fabian, Huge, Andreas, Hoffmeier, Andreas, Martens, Sven, Eckardt, Lars, Lange, Philipp S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996409/
https://ncbi.nlm.nih.gov/pubmed/30003094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3694362
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