Co-administered Tag-Less Toxoid Fusion 3xSTa(N12S)-mnLT(R192G/L211A) and CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) Induce Neutralizing Antibodies to 7 Adhesins (CFA/I, CS1-CS6) and Both Enterotoxins (LT, STa) of Enterotoxigenic Escherichia coli (ETEC)

Enterotoxigenic Escherichia coli (ETEC) bacteria remain a leading cause of children's diarrhea and travelers' diarrhea. Vaccines that induce antibodies to block ETEC bacterial adherence and to neutralize toxin enterotoxicity can be effective against ETEC-associated diarrhea. Recent studies...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Duan, Qiangde, Lu, Ti, Garcia, Carolina, Yañez, Coraima, Nandre, Rahul M., Sack, David A., Zhang, Weiping
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996201/
https://ncbi.nlm.nih.gov/pubmed/29922268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01198
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