Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration

Background: Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Inflammatory cytokines in the peripheral immune system can induce neuroinflammation in central nervous system (CNS). Whether the peripheral immune system is involved in PD is unclear. The pres...

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Dades bibliogràfiques
Publicat a:Front Aging Neurosci
Autors principals: Yan, Aijuan, Zhang, Yu, Lin, Jingya, Song, Lu, Wang, Xijin, Liu, Zhenguo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996129/
https://ncbi.nlm.nih.gov/pubmed/29922149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00160
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