Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration

Background: Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Inflammatory cytokines in the peripheral immune system can induce neuroinflammation in central nervous system (CNS). Whether the peripheral immune system is involved in PD is unclear. The pres...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Yan, Aijuan, Zhang, Yu, Lin, Jingya, Song, Lu, Wang, Xijin, Liu, Zhenguo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996129/
https://ncbi.nlm.nih.gov/pubmed/29922149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00160
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