Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration

Background: Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Inflammatory cytokines in the peripheral immune system can induce neuroinflammation in central nervous system (CNS). Whether the peripheral immune system is involved in PD is unclear. The pres...

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Bibliografiska uppgifter
I publikationen:Front Aging Neurosci
Huvudupphovsmän: Yan, Aijuan, Zhang, Yu, Lin, Jingya, Song, Lu, Wang, Xijin, Liu, Zhenguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996129/
https://ncbi.nlm.nih.gov/pubmed/29922149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00160
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